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Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH₂
Price range: $269.60 through $1,079.60
Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH₂
Mca-PLGL-Dpa-AR-amide is a very sensitive FRET substrate for continuous assays and in situ determination of the matrix metalloproteinase activity. Cleavage at the Gly-Leu bond separates the highly fluorescent Mca group from the efficient 2,4-dinitrophenyl quencher, resulting in an increase in fluorescence intensity. The kcat/Km values for the punctuated metalloproteinase (MMP-7) and for gelatinase (MMP-2), e.g., are 1.7·10⁵ and 6.3·10⁵ M⁻¹s⁻¹, respectively.
| Pack size available | 1mg, 1mg (CHF 269.60), 5mg, 5mg (CHF 1,079.60) |
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